The preparation of fluorescence-quenched probes for use in the characterization of human factor Xa substrate binding domains.
نویسندگان
چکیده
The preparation and characterization by LCMS of a library of 55 fluorescence- quenched peptides is described. The peptides bear a terminal anthranilamide fluorophore and a penultimate 2,4-dinitrophenyl-L-lysine quencher, and will be used to probe the substrate binding domain of the human blood coagulation enzyme, factor Xa.
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ورودعنوان ژورنال:
- Molecules
دوره 9 6 شماره
صفحات -
تاریخ انتشار 2004